Decreased Gross Motor, Working Memory, and Adaptive Behavior in Children with Congenital Adrenal Hyperplasia

Pediatric patients with CAH due to 21OHD exhibit distinct, age-dependent developmental deficits, with infants and toddlers displaying lower gross motor performance, and children exhibiting decreased auditory working memory and adaptive behavior skills. These findings suggest that early signs of developmental deficits in CAH may emerge at a younger age than previously recognized, emphasizing the role of clinical factors inherent to the disease.