Six-Year Outcomes After Transcatheter vs Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis
The 6-year results from the Evolut Low Risk trial show no significant difference in the composite endpoint of all-cause mortality or disabling stroke. At 6 and 7 years, the TAVR arm had a higher reintervention rate compared with surgery, driven by an increased incidence of aortic regurgitation. (Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients; NCT02701283).
Authors
- Ray Matthews (ORCID: https://orcid.org/0000-0002-7309-5069)
- Anuj Gupta (ORCID: https://orcid.org/0000-0003-1655-3745)
- Timothy Byrne (ORCID: https://orcid.org/0000-0002-2550-9335)
- Jon R. Resar (ORCID: https://orcid.org/0000-0001-9163-5420)
- Jonathan A. Rapp
- Robert Gooley
- Thomas Noel
- Eric Horlick (ORCID: https://orcid.org/0000-0003-1303-0586)
- Ayman Iskander
- Sameer A Gafoor
- W. A. L. Tonino
- George L. Zorn
- Frank P. Ittleman
- Anthony J. Rousou
- Antony Walton (ORCID: https://orcid.org/0000-0002-9173-5904)
- Leonardus Timmers
- Apurva Vyas (ORCID: https://orcid.org/0000-0001-9289-9508)
- Marie-France Poulin
- Visha Dev
- Bruce Rutkin
- Forrest Jn
- Sanjeevan Pasupati (ORCID: https://orcid.org/0000-0001-6417-493X)
- Shikhar Agarwal (ORCID: https://orcid.org/0000-0001-9101-1431)
- Bart Jensen
- Howard K. Song (ORCID: https://orcid.org/0000-0002-4254-006X)
- John K. Forrest (ORCID: https://orcid.org/0000-0003-4079-3482)
- Joseph A. Kozina
- Murali Muppala
- Kevin Lacappelle
- Robert C. Stoler (ORCID: https://orcid.org/0000-0002-8946-0163)
- Michael J. Reardon (ORCID: https://orcid.org/0000-0002-2880-6132)
- David Heimansohn
- William Merhi (ORCID: https://orcid.org/0009-0009-4075-9082)
- Jeffrey Newman
- Merick Kirshner
- Stephane Leung
- Jeffrey M. Sparling
- Ajanta De
- Arnaud Sudre
- Atul Chawla
- Paul S. Teirstein
- S. Mary Lilly
- Firas Zahr
- Gerald Yong
- Ken Kozuma
- Eric Lehr
- Rodrigo Bagur
- Peter Knight
- Joseph Coselli
- Ashequl Islam
- Michael Reardon
- Stanley Chetcuti
- Frederick Ling
- Josep Rodes-Cabau
- Gregory Rushing
- Donald Netherland
- Thomas Hovasse
- Ibrahim Sultan
- John Crouch
- Samin Sharma
- Peter Tadros
- Michele Gallo
- Shigeru Miyagawa
- Thomas Davis
- Peter Brady
- Sam Radhakrishnan
- Vivek Rajagopal
- Ka Yan Lam
- David Fullerton
- Reda Ibrahim
- Robert C. Merritt
- Vikas Sharma
- Ignacio Inglessis Azuaje
- Daniel Steinberg
- Itaru Takamisawa
- Satsuki Fukushima
- Sanjay Batra
- C. Craig Elkins
- Michael Chu
- Steven Park
- Kenji Ando
- Bartley Griffith
- Kashish Goel
- G. Michael Deeb
- Stephen Fremes
- Tomas Salerno
- J Kevin Harrison
- Thomas Haldis
- Norio Tada
- Arun Kanmanthareddy
- Mubashir Mumtaz
- Steven J. Yakubov
- Pierre Berthoumieu
- Didier Tchétché
- David Adams
- Siamak Mohammadi
- Neal Kon
- Frederick Welt
- David I Müller
- Tanvir Bajwa
- J. Michael Tuchek
- Paul Sorajja
- Mark Bladergroen
- Guilherme Silva
- Arnaud Farge
- Seiji Yamazaki
- James Hermiller
- Newell Robinson
- John Messenger
- Basel Ramlawi
- Nicolas M. van Mieghem
- David Zhao
- Eduardo de Marchena
- Jorge Alvarez
- Peter Fail
- John Wang
- JULIAN III SMITH
- Gregory Fontana
- Michael DeFrain
- Kamal Khabbaz
- Shigeru Saito
- Neal Kleiman
- George Petrossian
- G. Chad Hughes
- Ravinay Bhindi
- Marc Katz
- Vaughn A. Starnes
- Serguei Melnitchouk
- Raymond Cartier
Institutions
- OhioHealth (US)
- Houston Methodist (US)
- Riverside Methodist Hospital (US)
- Yale University (US)
- Michigan Medicine (US)
Publication Details
- Journal
- Journal of the American College of Cardiology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.jacc.2026.02.5063
- Citations
- 2
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 60.13