Case Report: pembrolizumab monotherapy achieves durable disease control in a patient with BRAF V600E-mutant advanced lung adenocarcinoma and high PD-L1 expression intolerant to BRAF/MEK inhibition

Patients with advanced NSCLC and <i>BRAF</i> mutations who cannot tolerate targeted therapy are expected to benefit from immunotherapy.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-16
DOI
https://doi.org/10.3389/fonc.2026.1720971
Primary Topic
Melanoma and MAPK Pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

Case Report: pembrolizumab monotherapy achieves durable disease control in a patient with BRAF V600E-mutant advanced lung adenocarcinoma and high PD-L1 expression intolerant to BRAF/MEK inhibition

Rong Zhou, Chunlai Feng, Wei Zhao
Frontiers in Oncology
Melanoma and MAPK Pathways
article

Case Report: pembrolizumab monotherapy achieves durable disease control in a patient with BRAF V600E-mutant advanced lung adenocarcinoma and high PD-L1 expression intolerant to BRAF/MEK inhibition

Rong Zhou, Chunlai Feng, Wei Zhao
article en

Abstract

Patients with advanced NSCLC and <i>BRAF</i> mutations who cannot tolerate targeted therapy are expected to benefit from immunotherapy.

Frontiers in OncologyVol. 16
Soochow University (CN)
Good health and well-being
Openalex Percentile: Top 55%
Melanoma and MAPK Pathways
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