Novel Plasma Proteomic Markers and Risk of Venous Thromboembolism
We identified several novel plasma proteins for VTE that reflect biological processes outside established VTE pathophysiology, including extracellular matrix regulation, immunity, immune-vascular endothelium interactions, and vascular senescence. Results may provide new modifiable targets to improve VTE risk stratification, prevention, or treatment.
Authors
- Florian Thibord (ORCID: https://orcid.org/0000-0003-2229-8322)
- Christian Jonasson (ORCID: https://orcid.org/0000-0002-7694-6025)
- Thomas R. Austin
- Guning Liu
- Folsom Ar
- Rui Cao
- Rajat Deo
- Peter R. Ganz
- Kent D. Taylor
- Ruth F. Dubin
- Xumin Li
- Bruce M. Psaty
- John-Bjarne Hansen
- Sigrid K. Brækkan
- James S. Pankow
- Ron C. Hoogeveen
- Nicholas L. Smith
- Weihong Tang
- Weihua Guan
- Mary Cushman
- Kunihiro Matsushita
- Aixin Li
- Therese H. Nøst
- Eric Boerwinkle
- Jerome I. Rotter
Institutions
- University of Vermont (US)
- University of Minnesota (US)
- Johns Hopkins University (US)
- Inserm (FR)
- University of California, San Francisco (US)
- Baylor College of Medicine (US)
- University of Washington (US)
- Norwegian University of Science and Technology (NO)
- Levanger Hospital (NO)
- UCLA Medical Center (US)
- VA Office of Research and Development (US)
- Kaiser Permanente Washington Health Research Institute (US)
- Bordeaux Population Health (FR)
- Department of Health (TW)
- University of Minnesota Medical Center (US)
- Thrombosis Research Institute (GB)
- Minnesota Department of Health (US)
- UiT The Arctic University of Norway (NO)
- University of Pennsylvania (US)
- The University of Texas Southwestern Medical Center (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Circulation
- Published
- 2026-02-16
- DOI
- https://doi.org/10.1161/circulationaha.125.074493
- Primary Topic
- Advanced Proteomics Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00