Intra-pancreatic fat deposition links to widespread systemic health risks: UK Biobank prospective cohort study
Limited research exists on the systemic effects of IPFD. Pancreatic fat deposition independently raises risk for 12 multi-system diseases. A 7.35% pancreatic fat threshold can guide clinical screening and prevention.
Authors
- Dan Wu (ORCID: https://orcid.org/0000-0001-6117-5099)
- Xiaxiao Yan (ORCID: https://orcid.org/0000-0001-5153-0528)
- Yingyu Pan (ORCID: https://orcid.org/0009-0007-6817-1219)
- Jiarui Mi (ORCID: https://orcid.org/0000-0001-6498-3817)
- Yanna Cai (ORCID: https://orcid.org/0009-0004-7844-3941)
- Ziqi Wan (ORCID: https://orcid.org/0000-0003-1809-3404)
- Zhengye Liu
- Hanze Du
- Guanqiao Li
- Nan Zhao
- Venkata S. Akshintala
- Zhengyang Fan
- Jianing Li
- Xiaoyin Bai
Institutions
- Johns Hopkins University (US)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Health and Family Planning Commission (CN)
- Peking Union Medical College Hospital (CN)
- Sir Run Run Shaw Hospital (CN)
- Johns Hopkins Bayview Medical Center (US)
- Tibet Autonomous Region People's Hospital (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Insights into Imaging
- Published
- 2026-02-16
- DOI
- https://doi.org/10.1186/s13244-026-02206-7
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Chinese Academy of Medical Sciences
- Peking Union Medical College Hospital
- Peking Union Medical College
- National Key Research and Development Program of China
- Division of Undergraduate Education