Comparative cardioprotective effects of Kuanxiong Aerosol and its individual components in a rat model of acute myocardial infarction
KXA's cardioprotection stems from the synergistic action of its components targeting ischemia, fibrosis, inflammation, and cardiac dysfunction. This study provides evidence supporting the cardioprotective potential of low-dose, multi-component KXA, indicating that such balanced formulations may offer broader benefits than high-dose or single-agent approaches. Further research is needed to elucidate the molecular mechanisms and refine the formulation for clinical translation.
Authors
- Xiaokang Peng (ORCID: https://orcid.org/0000-0002-0015-9447)
- Yuan-hang Zheng
- Xiaojing Fan (ORCID: https://orcid.org/0000-0001-5159-6674)
- Kai Qian
- Yefeng Chen (ORCID: https://orcid.org/0000-0003-1333-8097)
- Yang-yang Zhu
- Tao Yang
- Yu Tang
- Jin-ting Zhang
- Meng-meng Xu
- Yi Luo
Institutions
- Zhejiang Pharmaceutical College (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Pharmaceutical Biology
- Published
- 2026-02-15
- DOI
- https://doi.org/10.1080/13880209.2026.2626099
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 0.00