Lacticaseibacillus rhamnosus B6 alleviates metabolic dysfunction-associated fatty liver disease by suppressing intestinal LPS synthesis and regulating lipid metabolism

These findings demonstrate that <i>L. rhamnosus</i> B6 is a promising probiotic for MAFLD alleviation via dual mechanisms of attenuating inflammation and regulating lipid metabolism. This study provides compelling evidence for the specific protective effects of <i>L. rhamnosus</i> B6 against MAFLD and offers a novel probiotic-based therapeutic strategy for MAFLD.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-02-16
DOI
https://doi.org/10.3389/fendo.2026.1755982
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00

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article

Lacticaseibacillus rhamnosus B6 alleviates metabolic dysfunction-associated fatty liver disease by suppressing intestinal LPS synthesis and regulating lipid metabolism

Chunping You, Danqi Wang, Zhengjun WU, Jin HAN et al.
Frontiers in Endocrinology
Gut microbiota and health
article

Lacticaseibacillus rhamnosus B6 alleviates metabolic dysfunction-associated fatty liver disease by suppressing intestinal LPS synthesis and regulating lipid metabolism

Chunping You, Danqi Wang, Zhengjun WU, Jin HAN, Xiaohua Wang, Jing Wang
article en

Abstract

These findings demonstrate that <i>L. rhamnosus</i> B6 is a promising probiotic for MAFLD alleviation via dual mechanisms of attenuating inflammation and regulating lipid metabolism. This study provides compelling evidence for the specific protective effects of <i>L. rhamnosus</i> B6 against MAFLD and offers a novel probiotic-based therapeutic strategy for MAFLD.

Frontiers in EndocrinologyVol. 17
Dairy Management (US)
Natural Science Foundation of Shanghai
Good health and well-being
Openalex Percentile: Top 55%
Gut microbiota and health
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