Genetic association between PCSK9 and coronary artery calcification mediated by inflammatory cytokines

Inhibition of PCSK9 may effectively slow the progression of coronary artery calcification, with inflammatory mediators such as FGF23 playing key regulatory roles in this process.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2026-02-16
DOI
https://doi.org/10.3389/fcvm.2026.1767013
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
0.00

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article

Genetic association between PCSK9 and coronary artery calcification mediated by inflammatory cytokines

Xinyi Hu, Liang Chen, Weijian Wang, Chen Zongzheng et al.
Frontiers in Cardiovascular Medicine
Lipoproteins and Cardiovascular Health
article

Genetic association between PCSK9 and coronary artery calcification mediated by inflammatory cytokines

Xinyi Hu, Liang Chen, Weijian Wang, Chen Zongzheng, Li Wang, Jiangping Ye
article en

Abstract

Inhibition of PCSK9 may effectively slow the progression of coronary artery calcification, with inflammatory mediators such as FGF23 playing key regulatory roles in this process.

Frontiers in Cardiovascular MedicineVol. 13
Anhui Medical University (CN), Second Affiliated Hospital of Nanjing Medical University (CN), Pingjin Hospital (CN)
Jiangsu University
Good health and well-being
Openalex Percentile: Top 55%
Lipoproteins and Cardiovascular Health
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