Temporal trajectory of plasma miRNA during the peri-implantation stage: comparing implantation success and failure in single frozen–thawed blastocyst transfers

Understanding the dynamic landscape changes of the miRNA transcriptome in individuals with implantation failure will help identify dynamic biomarkers from ovulation to the post-implantation stage, providing new insights into the pathological mechanisms of implantation failure and facilitating the research and development of new therapies in the clinical setting.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-02-16
DOI
https://doi.org/10.3389/fendo.2026.1708664
Primary Topic
Reproductive System and Pregnancy
Type
article
Field-Weighted Citation Impact
0.00

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article

Temporal trajectory of plasma miRNA during the peri-implantation stage: comparing implantation success and failure in single frozen–thawed blastocyst transfers

Hongya Yang, He Xiao, Ju Yk, X. Wang et al.
Frontiers in Endocrinology
Reproductive System and Pregnancy
article

Temporal trajectory of plasma miRNA during the peri-implantation stage: comparing implantation success and failure in single frozen–thawed blastocyst transfers

Hongya Yang, He Xiao, Ju Yk, X. Wang, Juan Zhou, Yue Liang, Jianlei Huang, J Wu, Li Hai, Xiang Xiao, Shuqiang Chen, Lingyin Kong, Yuan Ma, Ni Jin, Lu Wang, Xiuyu Feng, Bo Liang
article en

Abstract

Understanding the dynamic landscape changes of the miRNA transcriptome in individuals with implantation failure will help identify dynamic biomarkers from ovulation to the post-implantation stage, providing new insights into the pathological mechanisms of implantation failure and facilitating the research and development of new therapies in the clinical setting.

Frontiers in EndocrinologyVol. 17
Jiangsu University (CN), Shanghai Jiao Tong University (CN), The Medical Device (United Kingdom) (GB), Tang Du Hospital (CN), Air Force Medical University (CN)
National Key Research and Development Program of China
Good health and well-being
Openalex Percentile: Top 53%
Reproductive System and Pregnancy
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