Identifiability for Gaussian Processes with Holomorphic Kernels

Gaussian processes (GPs) are widely recognized for their robustness and flexibility across various domains, including machine learning, analysis of time series, spatial statistics, and biomedicine. In addition to their common usage in regression tasks, GP kernel parameters are frequently interpreted in various applications. For example, in spatial transcriptomics, estimated kernel parameters are used to identify spatial variable genes, which exhibit significant expression patterns across different tissue locations. However, before these parameters can be meaningfully interpreted, it is essential to establish their identifiability. Existing studies of GP parameter identifiability have focused primarily on Matérn-type kernels, as their spectral densities allow for more established mathematical tools. In many real-world applications, particuarly in time series analysis, other kernels such as the squared exponential, periodic, and rational quadratic kernels, as well as their combinations, are also widely used. These kernels share the property of being holomorphic around zero, and their parameter identifiability remains underexplored. In this paper, we bridge this gap by developing a novel theoretical framework for determining kernel parameter identifiability for kernels holomorphic near zero. Our findings enable practitioners to determine which parameters are identifiable in both existing and newly constructed kernels, supporting application-specific interpretation of the identifiable parameters, and highlighting non-identifiable parameters that require careful interpretation.

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Publication Details

Journal
Europe PMC (PubMed Central)
Published
2025-04-01
Primary Topic
Gaussian Processes and Bayesian Inference
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article

Identifiability for Gaussian Processes with Holomorphic Kernels

Didong Li, Ameer Qaqish
Europe PMC (PubMed Central)
Gaussian Processes and Bayesian Inference
article

Identifiability for Gaussian Processes with Holomorphic Kernels

Didong Li, Ameer Qaqish
article en

Abstract

Gaussian processes (GPs) are widely recognized for their robustness and flexibility across various domains, including machine learning, analysis of time series, spatial statistics, and biomedicine. In addition to their common usage in regression tasks, GP kernel parameters are frequently interpreted in various applications. For example, in spatial transcriptomics, estimated kernel parameters are used to identify spatial variable genes, which exhibit significant expression patterns across different tissue locations. However, before these parameters can be meaningfully interpreted, it is essential to establish their identifiability. Existing studies of GP parameter identifiability have focused primarily on Matérn-type kernels, as their spectral densities allow for more established mathematical tools. In many real-world applications, particuarly in time series analysis, other kernels such as the squared exponential, periodic, and rational quadratic kernels, as well as their combinations, are also widely used. These kernels share the property of being holomorphic around zero, and their parameter identifiability remains underexplored. In this paper, we bridge this gap by developing a novel theoretical framework for determining kernel parameter identifiability for kernels holomorphic near zero. Our findings enable practitioners to determine which parameters are identifiable in both existing and newly constructed kernels, supporting application-specific interpretation of the identifiable parameters, and highlighting non-identifiable parameters that require careful interpretation.

Europe PMC (PubMed Central)
Openalex Percentile: Top 14%
Gaussian Processes and Bayesian Inference
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Identifiability for Gaussian Processes with Holomorphic Kernels — Didong Li, Ameer Qaqish · Europe PMC (PubMed Central) (2025) | TGRS Research Map | TGRS