Metabolomics-Based Study: Effects of Fructose, Glucose, and Mannose on Islet Cells and Change of Serum Markers in Streptozotocin-Induced Diabetic Rats
This experiment systematically revealed the differential effects of glucose, fructose, and mannose on the structural protection and metabolic pathways of rat pancreatic islets through metabolomics and histopathological analyses, providing an important theoretical basis for diabetic nutritional intervention and drug target development.
Authors
- Xiaomei Long
- Yuan Fan
- Shuang Guo (ORCID: https://orcid.org/0000-0002-7344-6121)
- Tao Liu (ORCID: https://orcid.org/0000-0002-7710-7557)
- Rong Li
- Jianxing Gu
- Zhusheng Tang
- Lijun Zhang
- Fangfang Chen
- Xueyan Li
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- Yunnan Provincial Hospital of Traditional Chinese Medicine (CN)
- Baoshan University (CN)
- Yunnan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Current Diabetes Reviews
- Published
- 2026-02-13
- DOI
- https://doi.org/10.2174/0115733998394170251129101618
- Primary Topic
- Diet, Metabolism, and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00