Encapsulated Enigma: Surgical Resolution of a Lingual Lipoma Affecting Oral Functions

Lingual lipomas are uncommon benign tumors, accounting for < 0.5% of all tongue neoplasms, due to the limited adipose tissue in this region. They are usually asymptomatic and slow growing, which may delay detection. We report the case of a 50-year-old man with a 4-year history of a painless, progressively enlarging submucosal mass on the ventral surface of the tongue. Clinical examination revealed a 3 × 3 cm sessile, yellowish, well-circumscribed lesion with tense-elastic consistency. Given its benign appearance, no preoperative imaging was performed. The lesion was surgically excised under local anesthesia, and histopathological analysis confirmed a conventional lipoma composed of mature adipocytes without atypia or lipoblasts. The patient recovered uneventfully and regained full oral function within 2 months. This case emphasizes the importance of including lingual lipomas in the differential diagnosis of tongue masses. It suggests that, in selected cases, clinical assessment alone may be sufficient for diagnosis and treatment planning.

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Journal
Clinical Case Reports
Published
2026-02-01
DOI
https://doi.org/10.1002/ccr3.71579
Primary Topic
Teratomas and Epidermoid Cysts
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article
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article

Encapsulated Enigma: Surgical Resolution of a Lingual Lipoma Affecting Oral Functions

Fabiana Battaglia, Mariausilia Franchina, Maria Lentini, Gabriele Delia et al.
Clinical Case Reports
Teratomas and Epidermoid Cysts
article

Encapsulated Enigma: Surgical Resolution of a Lingual Lipoma Affecting Oral Functions

Fabiana Battaglia, Mariausilia Franchina, Maria Lentini, Gabriele Delia, Ludovica Pepe, Francesco Stagno d’Alcontres
article en

Abstract

Lingual lipomas are uncommon benign tumors, accounting for < 0.5% of all tongue neoplasms, due to the limited adipose tissue in this region. They are usually asymptomatic and slow growing, which may delay detection. We report the case of a 50-year-old man with a 4-year history of a painless, progressively enlarging submucosal mass on the ventral surface of the tongue. Clinical examination revealed a 3 × 3 cm sessile, yellowish, well-circumscribed lesion with tense-elastic consistency. Given its benign appearance, no preoperative imaging was performed. The lesion was surgically excised under local anesthesia, and histopathological analysis confirmed a conventional lipoma composed of mature adipocytes without atypia or lipoblasts. The patient recovered uneventfully and regained full oral function within 2 months. This case emphasizes the importance of including lingual lipomas in the differential diagnosis of tongue masses. It suggests that, in selected cases, clinical assessment alone may be sufficient for diagnosis and treatment planning.

Clinical Case ReportsVol. 14(2)
University of Messina (IT), Istituto Ortopedico Gaetano Pini (IT)
Quality Education
Openalex Percentile: Top 55%
Teratomas and Epidermoid Cysts
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Encapsulated Enigma: Surgical Resolution of a Lingual Lipoma Affecting Oral Functions — Fabiana Battaglia, Mariausilia Franchina, et al. · Clinical Case Reports (2026) | TGRS Research Map | TGRS