Melatonin promotes embryonic development by enhancing tryptophan metabolism and NAD + synthesis
Exogenous melatonin acts through its receptors to modulate tryptophan metabolism and NAD<sup>+</sup> synthesis, demonstrating its potential as a key hormonal regulator of embryonic development and reproductive capacity.
Authors
- Guidong Yao (ORCID: https://orcid.org/0000-0002-7174-9989)
- Yingpu Sun
- Yue Kong
- Guang Yang
- Jun Zhai
- Junnan Fang
- Huihui Wang
- Qingling Yang
- Ran Jiang
- Chaoying Wang
Institutions
- Zhengzhou University (CN)
- National Center on Birth Defects and Developmental Disabilities (US)
- Yutong (China) (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- BMC Biology
- Published
- 2026-02-16
- DOI
- https://doi.org/10.1186/s12915-026-02549-z
- Primary Topic
- Circadian rhythm and melatonin
- Type
- article
- Field-Weighted Citation Impact
- 0.00