Associations between use of aspirin and magnetic resonance imaging‐derived liver fat and fibroinflammation

In this large population-based cohort, aspirin use was linked to reduced liver fat, but a small, clinically insignificant (i.e., <80 ms) increase in cT1. These findings suggest aspirin may mitigate steatosis through metabolic pathways but does not necessarily rapidly reverse fibroinflammatory injury.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2026-02-18
DOI
https://doi.org/10.1111/dom.70570
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Associations between use of aspirin and magnetic resonance imaging‐derived liver fat and fibroinflammation

Pinelopi Manousou, Jun Liu, Chioma N Izzi-Engbaeya, Qi Feng
Diabetes Obesity and Metabolism
Liver Disease Diagnosis and Treatment
article

Associations between use of aspirin and magnetic resonance imaging‐derived liver fat and fibroinflammation

Pinelopi Manousou, Jun Liu, Chioma N Izzi-Engbaeya, Qi Feng
article en

Abstract

In this large population-based cohort, aspirin use was linked to reduced liver fat, but a small, clinically insignificant (i.e., <80 ms) increase in cT1. These findings suggest aspirin may mitigate steatosis through metabolic pathways but does not necessarily rapidly reverse fibroinflammatory injury.

Diabetes Obesity and Metabolism
Imperial College Healthcare NHS Trust (GB), The George Institute for Global Health (GB), St Mary's Hospital (GB), The George Institute for Global Health (AU), Tongji Hospital (CN), St. Mary's Hospital (GB), Imperial College London (GB), Huazhong University of Science and Technology (CN)
National Institute for Health and Care Research, Department of Health and Social Care, NIHR Imperial Biomedical Research Centre
Good health and well-being
Openalex Percentile: Top 54%
Liver Disease Diagnosis and Treatment
DOIOpen Access PDFOpenAlex
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