Human Papillomavirus in Reproductive Health and Pregnancy: Clinical Implications, Outcomes, and a Comprehensive Review of Vaccination

Current evidence suggests that reproductive risks are more strongly associated with the treatment of HPV-related diseases than with HPV infection itself. Preventive strategies-especially HPV vaccination-remain central to reducing HPV-related disease burden. Although HPV vaccines are not routinely recommended during pregnancy, evidence supports the safety of inadvertent exposure around conception or during gestation, while potential long-term benefits of vaccination regarding reproductive health require further study.

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Publication Details

Journal
Vaccines
Published
2026-02-14
DOI
https://doi.org/10.3390/vaccines14020180
Primary Topic
Cervical Cancer and HPV Research
Type
article
Field-Weighted Citation Impact
0.00
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Human Papillomavirus in Reproductive Health and Pregnancy: Clinical Implications, Outcomes, and a Comprehensive Review of Vaccination

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Human Papillomavirus in Reproductive Health and Pregnancy: Clinical Implications, Outcomes, and a Comprehensive Review of Vaccination

Bilal Esat Temiz, Houssein El Hajj, Charlotte S. Goutallier, Hasan Volkan Ege, Zvi Vaknin, Joanna Kacperczyk‐Bartnik, Gökçen Ege, N Taumberger, Murat Gultekin, Utku Akgor, Maria Kyrgiou, Laura Burney Ellis, Reda Hemida
article en

Abstract

Current evidence suggests that reproductive risks are more strongly associated with the treatment of HPV-related diseases than with HPV infection itself. Preventive strategies-especially HPV vaccination-remain central to reducing HPV-related disease burden. Although HPV vaccines are not routinely recommended during pregnancy, evidence supports the safety of inadvertent exposure around conception or during gestation, while potential long-term benefits of vaccination regarding reproductive health require further study.

VaccinesVol. 14(2)
Imperial College Healthcare NHS Trust (GB), Mansoura University (EG), Medical University of Graz (AT), Medical University of Warsaw (PL), Mercy Hospital for Women (AU), Institut Gustave Roussy (FR), Graz University Hospital (AT), Memorial Ankara Hospital (TR), Assaf Harofeh Medical Center (IL), National Institute of Oncology (HU), Hospital of the Brothers of St. John of God (AT), Imperial College London (GB), Hacettepe University (TR)
Good health and well-being
Openalex Percentile: Top 54%
Cervical Cancer and HPV Research
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