Evaluation of Volumetric Reference Ranges for SPECT MPI Parameters and the Predictive Power of Dyssynchrony Parameters: A Cross-Sectional Study

Sex- and age-specific reference ranges for gated SPECT MPI reveal clinically meaningful variation in ventricular function and dyssynchrony by diagnosis. Logistic regression findings indicate that conventional ventricular volumes and patient characteristics primarily drive stress systolic impairment, while dyssynchrony indices offer complementary but not independent prognostic value.