Jinwei Guben Formula (Jinwei Formula II) Modulates NeutrophilExtracellular Trap Formation and Enhances Glucocorticoid Efficacy inCOPD Through HDAC2 Regulation
JWGB may alleviate neutrophilic inflammation in COPD by inhibiting NET formation and upregulating HDAC2. Its synergy with glucocorticoids suggests potential as a steroid- sparing therapy.
Authors
- Jiahui Wu (ORCID: https://orcid.org/0009-0007-6778-6764)
- Wenjuan Zhang
- Hantao Zhao (ORCID: https://orcid.org/0000-0002-3600-8923)
- Deyu Kong
- Xiaomeng Cheng
Institutions
- Beijing University of Chinese Medicine (CN)
Publication Details
- Journal
- Current Computer - Aided Drug Design
- Published
- 2026-02-11
- DOI
- https://doi.org/10.2174/0115734099441592251222045407
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00