Prognostic significance of Ki-67 in grade 3A follicular lymphoma and development of a novel PFS nomogram

Grade 3A FL is characterized by marked clinical and biological heterogeneity. Our findings indicate that Ki-67 expression serves as a valuable prognostic marker that can inform therapeutic decision-making in patients with grade 3A FL. The proposed model integrating Ki-67 and clinical variables enhances PFS prediction and supports individualized treatment strategies for these patients.

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Publication Details

Journal
Annals of Hematology
Published
2026-02-16
DOI
https://doi.org/10.1007/s00277-026-06891-8
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Prognostic significance of Ki-67 in grade 3A follicular lymphoma and development of a novel PFS nomogram

Cunzhen Shi, Qi Zhao, Chao Zhao, Zhenchang Sun et al.
Annals of Hematology
Lymphoma Diagnosis and Treatment
article

Prognostic significance of Ki-67 in grade 3A follicular lymphoma and development of a novel PFS nomogram

Cunzhen Shi, Qi Zhao, Chao Zhao, Zhenchang Sun, Xinhua Wang, Ling Li, Yu Chang, Zhaoming Li, Mingzhi Zhang, Yilin Zhang, Xiaorui Fu, Xinyue Li, Lei Zhang, Xin Li, Xiaolong Wu
article en

Abstract

Grade 3A FL is characterized by marked clinical and biological heterogeneity. Our findings indicate that Ki-67 expression serves as a valuable prognostic marker that can inform therapeutic decision-making in patients with grade 3A FL. The proposed model integrating Ki-67 and clinical variables enhances PFS prediction and supports individualized treatment strategies for these patients.

Annals of HematologyVol. 105(4)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN), First Affiliated Hospital of Zhengzhou University (CN)
Peace, Justice and strong institutions
Openalex Percentile: Top 56%
Lymphoma Diagnosis and Treatment
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