Efficacy and Safety of Conventional Versus Super-bioavailable Itraconazole in Dermatophytic Infections: A Prospective Randomized Comparative Study

SB-ITZ and C-ITZ showed comparable overall efficacy in dermatophytosis. SB-ITZ demonstrated a modest clinical advantage in recalcitrant cases with better tolerability. Treatment duration, adherence, and hygiene practices remain key determinants of long-term outcomes.

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Publication Details

Journal
Cureus
Published
2026-02-15
DOI
https://doi.org/10.7759/cureus.103654
Primary Topic
Nail Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and Safety of Conventional Versus Super-bioavailable Itraconazole in Dermatophytic Infections: A Prospective Randomized Comparative Study

Sakshi Sahni, Sana Islahi, Amrita Upadhyaya, K Geetha
Cureus
Nail Diseases and Treatments
article

Efficacy and Safety of Conventional Versus Super-bioavailable Itraconazole in Dermatophytic Infections: A Prospective Randomized Comparative Study

Sakshi Sahni, Sana Islahi, Amrita Upadhyaya, K Geetha
article en

Abstract

SB-ITZ and C-ITZ showed comparable overall efficacy in dermatophytosis. SB-ITZ demonstrated a modest clinical advantage in recalcitrant cases with better tolerability. Treatment duration, adherence, and hygiene practices remain key determinants of long-term outcomes.

CureusVol. 18(2)
Indira Gandhi Agricultural University (IN), ESIC Hospital (IN), ESIC Hospital (IN), All India Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 54%
Nail Diseases and Treatments
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