IFN‐γ Driven Hepatic Injury Exacerbates Mortality in NK/T‐Cell Lymphoma‐Associated Hemophagocytic Lymphohistiocytosis
The GSD index emerges as a robust prognostic tool for NK/T-HLH patients with hepatic dysfunction, reflecting underlying IFN-γ-mediated immunopathology. Early intervention with anti-IFN-γ monoclonal antibody may improve clinical outcomes in this high-risk subgroup.
Authors
- Jiajia Liu (ORCID: https://orcid.org/0000-0002-5471-6392)
- Jun Shi (ORCID: https://orcid.org/0000-0002-6880-6030)
- Haifang Hang
- Lingfei Wei (ORCID: https://orcid.org/0000-0001-5035-4817)
- Yuyang Pang
- Liyuan Ma
- Yehua Yu
- Hui Zhou
Institutions
- Shanghai Ninth People's Hospital (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/cam4.71606
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00