Killing the Undead: Can Senolytics Eradicate Zombie Cells and Reverse Aging?

This literature review examines the biological impact of senescent cells, often termed "zombie cells" on aging and the development of chronic disease. The review synthesizes recent preclinical and clinical research concerning cellular senescence and the Senescence-Associated Secretory Phenotype (SASP), which drives inflammation and tissue degeneration.

Authors

Mahenoor Rana

Publication Details

Journal: Zenodo (CERN European Organization for Nuclear Research)
Published: 2026-02-15
DOI: https://doi.org/10.5281/zenodo.18645359
Primary Topic: Telomeres, Telomerase, and Senescence
Type: article
Field-Weighted Citation Impact: 0.00

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article

Killing the Undead: Can Senolytics Eradicate Zombie Cells and Reverse Aging?

Mahenoor Rana

Feb 15, 2026

Zenodo (CERN European Organization for Nuclear Research)

Telomeres, Telomerase, and Senescence

article

Killing the Undead: Can Senolytics Eradicate Zombie Cells and Reverse Aging?

Mahenoor Rana

February 15, 2026article en

Abstract

Zenodo (CERN European Organization for Nuclear Research)

Openalex Percentile: Top 53%

Telomeres, Telomerase, and Senescence

DOI Open Access PDF OpenAlex

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Killing the Undead: Can Senolytics Eradicate Zombie Cells and Reverse Aging? — Mahenoor Rana · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS