The Presence of Non‐HLA Antibody With DSA Is Associated With Moderate to Severe T Cell‐Mediated Rejection in Liver Transplant Recipients

Non-HLA antibodies to AT1R or the Luminex panel are associated with MS-TCMR in LTx biopsies. The incidence of MS-TCMR is higher when non-HLA antibodies are present concomitantly with DSA, indicating an additive effect. Further studies are warranted to investigate the utility of routinely monitoring DSA and non-HLA antibodies in LTx recipients.

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Publication Details

Journal
Clinical Transplantation
Published
2026-02-01
DOI
https://doi.org/10.1111/ctr.70480
Primary Topic
Renal Transplantation Outcomes and Treatments
Type
article
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article

The Presence of Non‐HLA Antibody With DSA Is Associated With Moderate to Severe T Cell‐Mediated Rejection in Liver Transplant Recipients

Q. Xu, Nigar Khurram, Carol Bentlejewski, Adriana Zeevi et al.
Clinical Transplantation
Renal Transplantation Outcomes and Treatments
article

The Presence of Non‐HLA Antibody With DSA Is Associated With Moderate to Severe T Cell‐Mediated Rejection in Liver Transplant Recipients

Q. Xu, Nigar Khurram, Carol Bentlejewski, Adriana Zeevi, Anthony J. Demetris
article en

Abstract

Non-HLA antibodies to AT1R or the Luminex panel are associated with MS-TCMR in LTx biopsies. The incidence of MS-TCMR is higher when non-HLA antibodies are present concomitantly with DSA, indicating an additive effect. Further studies are warranted to investigate the utility of routinely monitoring DSA and non-HLA antibodies in LTx recipients.

Clinical TransplantationVol. 40(2)
University of Pittsburgh (US), University of Pittsburgh Medical Center (US)
Openalex Percentile: Top 54%
Renal Transplantation Outcomes and Treatments
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