Recurrent Mental Cutaneous Metastases Secondary to Bilateral Renal Cell Carcinoma

Renal cell carcinoma (RCC) is a common cancer of the urinary tract that continues to increase in incidence. With advances in imaging, RCC is being detected more frequently and at earlier stages. However, metastatic disease remains a common concern, resulting in worse prognoses. Common sites of metastases include the lungs, bone, lymph nodes, liver, brain, and adrenal glands. Bladder metastases are rare, with fewer than a hundred cases reported in the literature. Cutaneous metastases are also uncommon but have been reported. The case presented is a unique account of bilateral RCC with the development of both bladder and cutaneous metastases in the setting of prolonged survival. One treatment option for cutaneous metastases is surgical resection, as described in this case. However, based on the refractory course observed in this case, surgical resection alone may be insufficient in preventing recurrence, underscoring the need for future research investigating multimodal approaches such as combination therapy with radiation or immunotherapy. This patient went on to receive hospice care, further highlighting the relationship between metastatic disease and worsening prognoses.

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Publication Details

Journal
Cureus
Published
2026-02-15
DOI
https://doi.org/10.7759/cureus.103673
Primary Topic
Cancer Diagnosis and Treatment
Type
article
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article

Recurrent Mental Cutaneous Metastases Secondary to Bilateral Renal Cell Carcinoma

Javier Corral, Chase E Green, Monica Botros, Jessica L Hoffman
Cureus
Cancer Diagnosis and Treatment
article

Recurrent Mental Cutaneous Metastases Secondary to Bilateral Renal Cell Carcinoma

Javier Corral, Chase E Green, Monica Botros, Jessica L Hoffman
article en

Abstract

Renal cell carcinoma (RCC) is a common cancer of the urinary tract that continues to increase in incidence. With advances in imaging, RCC is being detected more frequently and at earlier stages. However, metastatic disease remains a common concern, resulting in worse prognoses. Common sites of metastases include the lungs, bone, lymph nodes, liver, brain, and adrenal glands. Bladder metastases are rare, with fewer than a hundred cases reported in the literature. Cutaneous metastases are also uncommon but have been reported. The case presented is a unique account of bilateral RCC with the development of both bladder and cutaneous metastases in the setting of prolonged survival. One treatment option for cutaneous metastases is surgical resection, as described in this case. However, based on the refractory course observed in this case, surgical resection alone may be insufficient in preventing recurrence, underscoring the need for future research investigating multimodal approaches such as combination therapy with radiation or immunotherapy. This patient went on to receive hospice care, further highlighting the relationship between metastatic disease and worsening prognoses.

CureusVol. 18(2)
Texas Tech University (US), The University of Texas at El Paso (US), University Medical Center of El Paso (US)
Good health and well-being
Openalex Percentile: Top 55%
Cancer Diagnosis and Treatment
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