Development of a National Indication Protocol for Proton Therapy in Patients With Seminoma Testis to Reduce the Risk on Subsequent Primary Cancers

We defined an NIPP for the selection of STPs for PT in the Netherlands, aimed to reduce the risk of SPC. According to this NIPP, about 75% of these patients qualify for PT. Further studies are required to allow inclusion of nononcological late effects as selection criteria in the NIPP.

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Publication Details

Journal
International Journal of Radiation Oncology*Biology*Physics
Published
2026-02-01
DOI
https://doi.org/10.1016/j.ijrobp.2026.02.207
Primary Topic
Testicular diseases and treatments
Type
article
Field-Weighted Citation Impact
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article

Development of a National Indication Protocol for Proton Therapy in Patients With Seminoma Testis to Reduce the Risk on Subsequent Primary Cancers

Johannes A. Langendijk, Mirko Unipan, Erik C. Schimmel, Charlotte L. Brouwer et al.
International Journal of Radiation Oncology*Biology*Physics
Testicular diseases and treatments
article

Development of a National Indication Protocol for Proton Therapy in Patients With Seminoma Testis to Reduce the Risk on Subsequent Primary Cancers

Johannes A. Langendijk, Mirko Unipan, Erik C. Schimmel, Charlotte L. Brouwer, Martine Franckena, Marianne A. A. de Jong, P. Bakker, Yvonne L.B. Klaver, Shafak Al Uwini, Peter F. Sinnige, Robert Jan Smeenk, Tom C.G. Budiharto, Maarten L.P. Dirkx, Wilma D Heemsbergen, Rob P. Coppes, Nienke Kuijsters, Ben Vanneste, Ewoud Schuit, Ada Oele, Steven JM Habraken, L. J. Boersma
article en

Abstract

We defined an NIPP for the selection of STPs for PT in the Netherlands, aimed to reduce the risk of SPC. According to this NIPP, about 75% of these patients qualify for PT. Further studies are required to allow inclusion of nononcological late effects as selection criteria in the NIPP.

International Journal of Radiation Oncology*Biology*Physics
University Medical Center Groningen (NL), Radboud University Nijmegen (NL), Leiden University Medical Center (NL), Catharina Ziekenhuis (NL), Erasmus MC (NL), University Medical Center Utrecht (NL), Instituut Verbeeten (NL), Radiotherapiegroep (NL), Erasmus MC Cancer Institute (NL), Radiotherapeutisch Instituut Friesland (NL), Maastro Clinic (NL)
Reduced inequalities
Openalex Percentile: Top 55%
Testicular diseases and treatments
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Development of a National Indication Protocol for Proton Therapy in Patients With Seminoma Testis to Reduce the Risk on Subsequent Primary Cancers — Johannes A. Langendijk, Mirko Unipan, et al. · International Journal of Radiation Oncology*Biology*Physics (2026) | TGRS Research Map | TGRS