Ultrafast in situ formation of antibiotic-free injectable hydrogel dressings with innate antibacterial activity and autolysis capacity for wound healing

The OSN hydrogel represents a significant advancement in antibacterial wound dressings, featuring robust tissue adhesion, controllable in-situ autolysis, and potent antibiotic-free antibacterial effects. This remarkable antibacterial therapeutic modality not only enhances the treatment of drug-resistant infections but also simplifies clinical wound management by eliminating the need for painful dressing changes, thereby supporting improved patient compliance and healing outcomes.