Cost‐effectiveness of <scp>cEK</scp> ‐preventive matched transfusion strategies for female transfusion recipients to prevent haemolytic disease of the foetus and newborn in the Dutch healthcare setting

Transfusion matching for c and K, but not E, is the most cost-effective strategy to prevent HDFN in the Dutch setting. Matching for E provides minimal health benefit at higher costs. These findings support revising current guidelines to cK-matching, ensuring optimal prevention of HDFN while reducing healthcare expenditures.

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Publication Details

Journal
Vox Sanguinis
Published
2026-02-15
DOI
https://doi.org/10.1111/vox.70212
Primary Topic
Blood groups and transfusion
Type
article
Field-Weighted Citation Impact
0.00
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article

Cost‐effectiveness of cEK ‐preventive matched transfusion strategies for female transfusion recipients to prevent haemolytic disease of the foetus and newborn in the Dutch healthcare setting

Claudia C. Folman, Jessie S. Luken, Elske M. E. van den Akker‐van Marle, Masja de Haas et al.
Vox Sanguinis
Blood groups and transfusion
article

Cost‐effectiveness of cEK ‐preventive matched transfusion strategies for female transfusion recipients to prevent haemolytic disease of the foetus and newborn in the Dutch healthcare setting

Claudia C. Folman, Jessie S. Luken, Elske M. E. van den Akker‐van Marle, Masja de Haas, Amy Bouman
article en

Abstract

Transfusion matching for c and K, but not E, is the most cost-effective strategy to prevent HDFN in the Dutch setting. Matching for E provides minimal health benefit at higher costs. These findings support revising current guidelines to cK-matching, ensuring optimal prevention of HDFN while reducing healthcare expenditures.

Vox Sanguinis
Leiden University Medical Center (NL), Sanquin (NL), Amsterdam University Medical Centers (NL)
Gender equality
Openalex Percentile: Top 54%
Blood groups and transfusion
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