Integrated Bioinformatics Analysis and Machine Learning to Identify Biomarkers and Fibroblast-related Features of Idiopathic PulmonaryFibrosis

We identified that STEAP2 plays an important regulatory role in IPF and developed a diagnostic model based on characteristic biomarkers. Overall, this research provides new insights into the pathogenesis of IPF from both biological and genetic perspectives, offering potential therapeutic targets for its treatment.

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Publication Details

Journal
Current Medicinal Chemistry
Published
2026-02-04
DOI
https://doi.org/10.2174/0109298673399689251110104124
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
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article

Integrated Bioinformatics Analysis and Machine Learning to Identify Biomarkers and Fibroblast-related Features of Idiopathic PulmonaryFibrosis

Guofeng Li, Jiayi Liu, Lijie Li, Jiajia Li et al.
Current Medicinal Chemistry
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

Integrated Bioinformatics Analysis and Machine Learning to Identify Biomarkers and Fibroblast-related Features of Idiopathic PulmonaryFibrosis

Guofeng Li, Jiayi Liu, Lijie Li, Jiajia Li, Xinru Fei, Dongkai Zhao, Yuhua Wen, Huiling Zhou
article en

Abstract

We identified that STEAP2 plays an important regulatory role in IPF and developed a diagnostic model based on characteristic biomarkers. Overall, this research provides new insights into the pathogenesis of IPF from both biological and genetic perspectives, offering potential therapeutic targets for its treatment.

Current Medicinal ChemistryVol. 33
Changchun University of Chinese Medicine (CN), The Affiliated Hospital to Changchun University of Chinese Medicine (CN)
No poverty
Openalex Percentile: Top 55%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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