Healthcare resource utilization and costs of letermovir for cytomegalovirus-prophylaxis after allogeneic hematopoietic cell transplantation in a real-world, multi-centre study in Germany
Our study demonstrated higher anti-CMV drug acquisition costs and overall direct treatment costs in patients receiving letermovir prophylaxis compared to controls. However, these higher costs are accompanied by significantly improved clinical outcomes.
Authors
- O. Penack
- Torsten Steinbrunn (ORCID: https://orcid.org/0000-0002-8793-9998)
- Andrés Rettig (ORCID: https://orcid.org/0000-0002-4004-3609)
- Annika Y. Claßen (ORCID: https://orcid.org/0000-0003-2905-5139)
- Maria J. G. T. Vehreschild (ORCID: https://orcid.org/0000-0003-0446-3224)
- Sabrina Kraus (ORCID: https://orcid.org/0000-0001-8954-4220)
- Claudia Wehr (ORCID: https://orcid.org/0000-0002-5037-6175)
- Daniel Teschner (ORCID: https://orcid.org/0000-0001-7351-8060)
- Sebastian Wingen‐Heimann (ORCID: https://orcid.org/0000-0002-4232-6944)
- Gesine Bug (ORCID: https://orcid.org/0000-0003-2359-131X)
- Corinna Hebermehl
- Sina M. Pütz
- Marie Engelhard
- J. Janne Vehreschild
- Igor-Wolfgang Blau
Institutions
- Goethe University Frankfurt (DE)
- Harvard University (US)
- University of Freiburg (DE)
- University of Cologne (DE)
- Johannes Gutenberg University Mainz (DE)
- University Medical Center Freiburg (DE)
- Frankfurt Institute for Advanced Studies (DE)
- FOM University of Applied Sciences for Economics and Management (DE)
- Humboldt-Universität zu Berlin (DE)
- Düsseldorf University Hospital (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Integrated Oncology (United States) (US)
- German Center for Infection Research (DE)
- Dana-Farber Cancer Institute (US)
- Universitätsklinikum Würzburg (DE)
- University Hospital Frankfurt (DE)
- Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- University Hospital Cologne (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- The European Journal of Health Economics
- Published
- 2026-02-16
- DOI
- https://doi.org/10.1007/s10198-025-01890-4
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitätsklinikum Köln