Prospective Phase 2 Trial: Long-term results of a salvage brachytherapy combined with interstitial hyperthermia as Re-Irradiation for locally recurrent prostate Carcinoma

Salvage brachytherapy with interstitial hyperthermia in local recurrent, previously irradiated, prostate cancer is effective with very low late toxicity. Since there are no meaningful randomized comparative studies available, it remains unclear whether the additional use of interstitial hyperthermia can further improve the effectiveness of salvage brachytherapy alone.

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Publication Details

Journal
Radiotherapy and Oncology
Published
2026-02-15
DOI
https://doi.org/10.1016/j.radonc.2026.111446
Primary Topic
Ultrasound and Hyperthermia Applications
Type
article
Field-Weighted Citation Impact
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article

Prospective Phase 2 Trial: Long-term results of a salvage brachytherapy combined with interstitial hyperthermia as Re-Irradiation for locally recurrent prostate Carcinoma

Stephan Kreppner, Andrzej Kukiełka, Ricarda Merten, Piotr Brandys et al.
Radiotherapy and Oncology
Ultrasound and Hyperthermia Applications
article

Prospective Phase 2 Trial: Long-term results of a salvage brachytherapy combined with interstitial hyperthermia as Re-Irradiation for locally recurrent prostate Carcinoma

Stephan Kreppner, Andrzej Kukiełka, Ricarda Merten, Piotr Brandys, Ewelina Gruszczyńska, Michael Lotter, Rainer Fietkau, Manfred Schmidt, Mateusz Dąbkowski, Vratislav Strnad, Oliver Josef Ott, Stefanie Corradini, Tomasz Dąbrowski, Annedore Renate Strnad, Anna Kulik
article en

Abstract

Salvage brachytherapy with interstitial hyperthermia in local recurrent, previously irradiated, prostate cancer is effective with very low late toxicity. Since there are no meaningful randomized comparative studies available, it remains unclear whether the additional use of interstitial hyperthermia can further improve the effectiveness of salvage brachytherapy alone.

Radiotherapy and OncologyVol. 218
Akademia Tarnowska (PL), National Institute of Oncology (HU), Krakow Cardiovascular Research Institute (PL), Comprehensive Cancer Center Erlangen (DE), The Maria Sklodowska-Curie National Research Institute of Oncology (PL)
Openalex Percentile: Top 56%
Ultrasound and Hyperthermia Applications
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