ESTIMATING THE PREVALENCE OF FAMILIAL HYPERCHOLESTEROLEMIA IN STROKE AND TRANSITORY ISCHEMIC ATTACK POPULATION: A SYSTEMATIC REVIEW AND META-ANALYSIS.

The evidence linking FH to stroke remains limited and highly heterogeneous, preventing firm quantitative conclusions. However, the available studies offer preliminary signals that FH may have relevance beyond cardiology and should be considered in discussions of cerebrovascular risk. Given the small number of studies and their methodological variability, further research with standardized diagnostic criteria and larger, well-designed cohorts is needed to clarify this relationship and to determine whether improved detection and management of FH in stroke populations could help reduce the broader burden of atherosclerotic disease.