ASSESSMENT OF CLINICAL SYMPTOMS OF ACUTE TOXICITY FOLLOWING THE IMPLANTATION OF A NANOCELLULOSE-BASED BIOCOMPOSITE.

The nanocellulose-based biocomposite did not exhibit pyrogenic activity when implanted into bone and soft tissues. Assessment of several behavioral acts and states revealed no statistically significant differences in locomotor and exploratory activity between the experimental and control groups. The analysis of the indicators shows that the tested substance does not exert an acute toxic effect on the nervous system.