Fats and Facts: A Meta-Analysis of Lipid Biomarkers in Endometrial Cancer
This meta-analysis establishes a significant association between dyslipidemia and endometrial cancer risk, with elevated triglycerides and LDL-C conferring increased risk while HDL-C appears protective. These findings support the integration of lipid profiling into EC risk assessment protocols and suggest the potential preventive value of lipid-modulating interventions. Further studies are needed to establish causality and evaluate therapeutic applications.
Authors
- Dan Alin Brebu
- Andreea-Adriana Neamțu (ORCID: https://orcid.org/0000-0002-5219-5466)
- Ionuţ Flaviu Faur (ORCID: https://orcid.org/0000-0001-6451-7461)
- Bogdan Totolici (ORCID: https://orcid.org/0009-0001-7655-5075)
- Amadeus Dobrescu (ORCID: https://orcid.org/0000-0001-5736-572X)
- Paul Pașca
- Ioana Adelina Clim
- Cătălin Prodan-Bărbulescu (ORCID: https://orcid.org/0000-0003-4348-5469)
- Cosmin Burta
- Ciprian Duta
- Carmen Neamtu
- Vlad Braicu
- Sergiu Florin Bara
Institutions
- Arad County Clinical Hospital (RO)
- Victor Babeș University of Medicine and Pharmacy Timișoara (RO)
- Vasile Goldis Western University of Arad (RO)
Publication Details
- Journal
- Life
- Published
- 2026-02-14
- DOI
- https://doi.org/10.3390/life16020330
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00