Evaluating the Feasibility of Using Historical Placebo Control in Osteoarthritis Trials

The findings indicate that replacing a real placebo group with a historical placebo in osteoarthritis RCTs is hardly feasible. These results underscore the complexity of placebo effects in osteoarthritis trials and the limitations of historical control data in this context.

Authors

Institutions

Publication Details

Journal
Epidemiologia
Published
2026-02-14
DOI
https://doi.org/10.3390/epidemiologia7010027
Primary Topic
Pain Management and Placebo Effect
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Evaluating the Feasibility of Using Historical Placebo Control in Osteoarthritis Trials

Anne-Françoise Donneau, Emma Barbeau
Epidemiologia
Pain Management and Placebo Effect
article

Evaluating the Feasibility of Using Historical Placebo Control in Osteoarthritis Trials

Anne-Françoise Donneau, Emma Barbeau
article en

Abstract

The findings indicate that replacing a real placebo group with a historical placebo in osteoarthritis RCTs is hardly feasible. These results underscore the complexity of placebo effects in osteoarthritis trials and the limitations of historical control data in this context.

EpidemiologiaVol. 7(1)
University of Liège (BE)
Good health and well-being
Openalex Percentile: Top 56%
Pain Management and Placebo Effect
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Evaluating the Feasibility of Using Historical Placebo Control in Osteoarthritis Trials — Anne-Françoise Donneau, Emma Barbeau · Epidemiologia (2026) | TGRS Research Map | TGRS