Visualization of oligomerization, clustering, and density transition of intrinsically disordered proteins
This study directly visualizes how Intrinsically Disordered Proteins form condensates, revealing a multi-step nucleation process that begins with single molecules and proceeds through intermediate clusters and density transition.
Authors
- Jia‐Ye Li
- Hao Wang (ORCID: https://orcid.org/0000-0001-6881-9977)
- Yi-hao Niu
- Yi-Qin Gao
Institutions
- Peking University (CN)
- Beijing National Laboratory for Molecular Sciences (CN)
- Imaging Center (US)
Publication Details
- Journal
- National Science Review
- Published
- 2026-02-13
- DOI
- https://doi.org/10.1093/nsr/nwag107
- Primary Topic
- Protein Structure and Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 0.00