PSMA-targeted fluorescent probe for NIR-II imaging in prostate cancer intraoperative navigation and tumor margin mapping
PSMA-12-IRDye800CW enables NIR-II fluorescence imaging-assisted intraoperative navigation and provides a quantitative, pathology-anchored readout for histopathological margin mapping in prostate cancer, supporting further clinical validation of this PSMA-targeted strategy for fluorescence-guided surgery and margin assessment.
Authors
- Jiedong Jia (ORCID: https://orcid.org/0000-0002-0400-2973)
- Dongwen Wang
- Gaohaer Kadeerhan
- Haozhe Tan
- Jiali Jin
- Wenmin Guo
- Ben Zhong Tang
- Jin Zhang
- Hong Guo
- Zhongji Jiang
- Zikuan Zhang
- Lin Zhang
- Bo Wu
- Jun Tian
Institutions
- Shanxi Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Southern University of Science and Technology (CN)
- National Cancer Center (US)
- Chinese University of Hong Kong, Shenzhen (CN)
- First Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Theranostics
- Published
- 2026-02-11
- DOI
- https://doi.org/10.7150/thno.117540
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chinese Academy of Medical Sciences
- Peking Union Medical College
- Sanming Project of Medicine in Shenzhen