Effects of home-based inspiratory muscle training on sympatho-vagal balance, quality of life, and inflammatory profile in patients with systemic sclerosis-associated interstitial lung disease
IMT significantly enhanced cardiac autonomic regulation along with improvements in respiratory function and sleep quality in SSc-ILD patients and demonstrated slight indications of an increased anti-inflammatory effect. These findings highlight IMT as a promising non-pharmacological intervention to improve autonomic function, offering potential cardioprotective and clinical benefits for SSc patients.
Authors
- Costanza Scatà (ORCID: https://orcid.org/0009-0006-0008-6766)
- Angelica Carandina (ORCID: https://orcid.org/0000-0002-7170-4852)
- Gabriel Dias Rodrigues (ORCID: https://orcid.org/0000-0002-9258-2954)
- Eleonora Tobaldini (ORCID: https://orcid.org/0000-0003-3627-8293)
- Beatrice Arosio
- Marco Vicenzi
- Chiara Bellocchi
- Lorenzo Beretta
- Nicola Montano
Institutions
- University of Milan (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Metropolitana Milanese (Italy) (IT)
Publication Details
- Journal
- European journal of medical research
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1186/s40001-026-03958-0
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00