Prognostic Scores for Liver Resection in Colorectal Metastases: Performance, Limitations, and Methodological Pitfalls—A Systematic Review and Meta-Analysis
The current survival prediction relies on scores with low reliability (C-index ≤ 0.65). Despite the abundance of available data, their heterogeneity and variable quality have limited their usability. Future research should prioritize the development of new prognostic tools and the standardization of prognostic modeling and reporting.
Authors
- Elisa Maria Ragaini (ORCID: https://orcid.org/0000-0003-1043-8690)
- Luca Viganò (ORCID: https://orcid.org/0000-0002-4108-4832)
- Luca Risi (ORCID: https://orcid.org/0009-0000-5485-3728)
- Elena Desiato
- Francesca Ieva
Institutions
- Humanitas University (IT)
- Human Technopole (IT)
- Humanitas Gavazzeni (IT)
- Politecnico di Milano (IT)
Publication Details
- Journal
- Cancers
- Published
- 2026-02-14
- DOI
- https://doi.org/10.3390/cancers18040625
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Associazione Italiana per la Ricerca sul Cancro