Dual antiplatelet therapy pretreatment in patients undergoing intravenous thrombolysis for acute ischemic stroke: a systematic review and meta-analysis of 296,854 patients
Prestroke DAPT was not associated with favorable functional outcome or reduced mortality after IVT and was associated with a higher risk of sICH when defined by NINDS criteria, with a 1% absolute risk increase.
Authors
- Mariana Letícia de Bastos Maximiano (ORCID: https://orcid.org/0009-0005-8359-6763)
- Lucas Pari Mitre (ORCID: https://orcid.org/0000-0003-0298-1052)
- Filipe Virgílio Ribeiro (ORCID: https://orcid.org/0000-0002-1091-6624)
- João Vítor Andrade Fernandes (ORCID: https://orcid.org/0000-0002-0619-4796)
- Ahmet Günkan (ORCID: https://orcid.org/0000-0002-6236-5633)
- Lucca Tamara Alves Carretta (ORCID: https://orcid.org/0009-0005-1942-2363)
- Paweł Łajczak (ORCID: https://orcid.org/0000-0003-0281-5417)
- Ocílio Ribeiro Gonçalves
- Fábio de Melo Franzoni
- Luciano Falcão
- João Victor Pereira Gonzalez
- Mariana Lee Han
Institutions
- University of Arizona (US)
- Medical University of Silesia (PL)
- Universidade Federal da Paraíba (BR)
- Centro Universitário Cesumar (BR)
- Universidade Federal do Piauí (BR)
- Centro Universitário Barão de Mauá (BR)
- Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória (BR)
- Faculdade de Ciências Médicas da Santa Casa de São Paulo (BR)
Publication Details
- Journal
- Neurological Research
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1080/01616412.2026.2629550
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00