Short-term linaclotide plus polyethylene glycol in patients at increased risk of inadequate bowel preparation: A randomized, double-blind, multicenter trial

A 2-day linaclotide regimen failed to improve the primary endpoints of bowel preparation adequacy or adenoma detection in high-risk patients.

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Publication Details

Journal
Digestive and Liver Disease
Published
2026-02-01
DOI
https://doi.org/10.1016/j.dld.2026.01.229
Primary Topic
Colorectal Cancer Screening and Detection
Type
article
Field-Weighted Citation Impact
0.00

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article

Short-term linaclotide plus polyethylene glycol in patients at increased risk of inadequate bowel preparation: A randomized, double-blind, multicenter trial

Zhiguo Liu, Ying Han, Hong Li, Yi-Xiang Wang et al.
Digestive and Liver Disease
Colorectal Cancer Screening and Detection
article

Short-term linaclotide plus polyethylene glycol in patients at increased risk of inadequate bowel preparation: A randomized, double-blind, multicenter trial

Zhiguo Liu, Ying Han, Hong Li, Yi-Xiang Wang, Nian Fang, Caixia Fan, Jiaqiang Dong, Yujie Jing, Lili Yuan, Hui Chen, Kun Zhuang
article en

Abstract

A 2-day linaclotide regimen failed to improve the primary endpoints of bowel preparation adequacy or adenoma detection in high-risk patients.

Digestive and Liver Disease
Nanchang University (CN), Shanxi Medical University (CN), Xian Central Hospital (CN), Third Affiliated Hospital of Nanchang University (CN), Third Hospital of Nanchang (CN), First Affiliated Hospital of Xi'an Jiaotong University (CN), Second Affiliated Hospital of Xi'an Jiaotong University (CN), Second Hospital of Shanxi Medical University (CN), Xijing Hospital (CN), Air Force Medical University (CN)
AstraZeneca
Openalex Percentile: Top 55%
Colorectal Cancer Screening and Detection
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