Integrative bioinformatics identifies NSCLC biomarkers associated with LPS metabolism and circadian disruption
This study identifies a novel gene signature linked to LPS metabolism and circadian disruption in NSCLC, with validated diagnostic utility and implications for tumor immune regulation. CACNA2D2 emerges as a key tumor suppressor, offering insights for early detection and targeted therapy development.
Authors
- Yunfeng Chen (ORCID: https://orcid.org/0000-0002-7534-0021)
- Qinghua Kong
- Yabin Li
- Ping Jiang
- Yifan Zhao
- Lichao Fan
Institutions
- Tongji University (CN)
- Shanghai Jiao Tong University (CN)
- Suzhou Kowloon Hospital (CN)
- Dahua Hospital (CN)
- Shanghai Pulmonary Hospital (CN)
- Tongji Hospital (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1016/j.tranon.2026.102699
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00