Exercise‐induced immune response in breast cancer patients during prehabilitation, neoadjuvant or adjuvant treatment: A systematic review and meta‐analysis

These meta-analyses suggest that exercise does not significantly alter immune function or markers of inflammation in BC patients during prehabilitation, adjuvant or neoadjuvant treatment. As no negative effect was observed, exercise appears to be safe and should be recommended to patients during cancer treatment because of its beneficial effects on quality of life, fatigue, cancer-related pain and survival.

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Publication Details

Journal
European Journal of Clinical Investigation
Published
2026-02-01
DOI
https://doi.org/10.1111/eci.70176
Primary Topic
Exercise and Physiological Responses
Type
article
Field-Weighted Citation Impact
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article

Exercise‐induced immune response in breast cancer patients during prehabilitation, neoadjuvant or adjuvant treatment: A systematic review and meta‐analysis

Jolien Hendrix, J. Nijs, Kenza Mostaqim, Eva Huysmans et al.
European Journal of Clinical Investigation
Exercise and Physiological Responses
article

Exercise‐induced immune response in breast cancer patients during prehabilitation, neoadjuvant or adjuvant treatment: A systematic review and meta‐analysis

Jolien Hendrix, J. Nijs, Kenza Mostaqim, Eva Huysmans, Joeri L. Aerts, Lore Dams, Astrid Lahousse, Christel Fontaine, Andrea Polli, Ishtiaq Ahmed, Simone Ubaghs, Yanthe Buntinx
article en

Abstract

These meta-analyses suggest that exercise does not significantly alter immune function or markers of inflammation in BC patients during prehabilitation, adjuvant or neoadjuvant treatment. As no negative effect was observed, exercise appears to be safe and should be recommended to patients during cancer treatment because of its beneficial effects on quality of life, fatigue, cancer-related pain and survival.

European Journal of Clinical InvestigationVol. 56(2)
Vrije Universiteit Brussel (BE), University of Antwerp (BE), Research Foundation - Flanders (BE), Antwerp University Hospital (BE), Pain in Motion (BE), Universitair Ziekenhuis Brussel (BE), Hasselt University (BE), University of Gothenburg (SE), KU Leuven (BE)
Good health and well-being
Openalex Percentile: Top 54%
Exercise and Physiological Responses
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Exercise‐induced immune response in breast cancer patients during prehabilitation, neoadjuvant or adjuvant treatment: A systematic review and meta‐analysis — Jolien Hendrix, J. Nijs, et al. · European Journal of Clinical Investigation (2026) | TGRS Research Map | TGRS