Chromosome-scale genome of the burrowing sea anemone Paracondylactis sinensis

Paracondylactis sinensis is a burrowing sea anemone inhabiting soft sediments along the Chinese coast, representing an ecologically and economically important actiniarian species. Despite its unique adaptations to hypoxia and sediment-associated stressors, genomic resources for burrowing sea anemones have been lacking. Here, we report a high-quality, chromosome-level genome assembly of P. sinensis. With PacBio HiFi long reads (39.77 × coverage), Illumina short reads, and Hi-C data, a 210.63 Mb genome with a contig N50 of 8.70 Mb and a scaffold N50 of 9.41 Mb was generated. A total of 93.44% of the assembly was anchored to 19 pseudo-chromosomes. BUSCO analysis indicated 95.91% completeness, confirming high assembly quality. Comprehensive annotation identified 19,420 protein-coding genes, of which 91.35% were functionally annotated. Repetitive elements accounted for 26.43% of the genome, with transposable elements representing 20.47%. This genome provides a crucial reference for understanding the genetic basis of environmental adaptation in P. sinensis and supports future efforts in its conservation, aquaculture, and bioactive compound exploration.