Host response biomarkers of tuberculosis recurrence and treatment failure
These sputum-independent biomarkers effectively identify TB disease, non-conversion and recurrence TB after EOT, whereas their utility in detecting TB reversion during treatment remains limited.
Authors
- Mkunde Chachage (ORCID: https://orcid.org/0000-0003-2196-1073)
- Kairaba Kanyi
- Gambia Sowe
- Basil Sambou
- Kavindhran Velen (ORCID: https://orcid.org/0000-0001-8577-3915)
- Olga Baranov
- Nelly Jinga (ORCID: https://orcid.org/0000-0001-6010-2867)
- Azeezat Sallahdeen
- Robert S. Wallis (ORCID: https://orcid.org/0000-0001-6152-5183)
- V. Jani Ilesh
- Lwitiho Sudi
- Daniel Mapamba (ORCID: https://orcid.org/0000-0001-5642-488X)
- Sanne Ian
- Binta Sarr
- Gavin Churchyard (ORCID: https://orcid.org/0000-0002-4269-3699)
- Salieu Barry
- Ulrich E. Schaible (ORCID: https://orcid.org/0000-0002-6638-7282)
- Bernadette Bauer
- Christof Geldmacher (ORCID: https://orcid.org/0000-0001-6777-7621)
- Celina Nhamuave
- Lyndel Singh
- Farzana Sathar (ORCID: https://orcid.org/0000-0002-8296-8554)
- Awa Touray (ORCID: https://orcid.org/0009-0006-2360-6955)
- Abhishek Bakuli (ORCID: https://orcid.org/0000-0001-5123-1974)
- Elmar Saathoff (ORCID: https://orcid.org/0000-0003-4874-380X)
- Cândido Azize
- Carla Madeira (ORCID: https://orcid.org/0000-0002-4252-203X)
- Caleb Muefong (ORCID: https://orcid.org/0000-0001-8817-9188)
- M Merker
- Fadzai Munedzimwe
- Shamanthi Jayasooriya (ORCID: https://orcid.org/0000-0002-1147-5744)
- Fidelina Cumbe Zekoll
- John D. Sutherland (ORCID: https://orcid.org/0000-0001-7099-4731)
- Alhaji Jobe
- I. Loum
- Celso Khosa (ORCID: https://orcid.org/0000-0001-6701-4202)
- Vânia Maphossa
- Momodou W. Jallow (ORCID: https://orcid.org/0000-0001-9748-538X)
- Khalide Azam (ORCID: https://orcid.org/0000-0002-9188-1207)
- Rohey Jallow
- Kathrin Held (ORCID: https://orcid.org/0000-0001-7057-6935)
- Luming Lin
- Emmanuel Sichone
- Mohammed Naim Rassool
- Mustapha Bah
- Nádia Sitoe (ORCID: https://orcid.org/0000-0001-7310-8221)
- Abi-Janet Riley
- Julieth Lalashowi (ORCID: https://orcid.org/0000-0002-6213-5213)
- Elimina Siyame
- Cláudio Abujate
- Nilesh Bhatt (ORCID: https://orcid.org/0000-0002-8389-7786)
- Georgetta K. Daffeh
- Simon D. Donkor
- Viola Dreyer
- Lindsay Zurba
- Cristovão Matusse
- Lamin Bah
- Olena Ivanova
- Abisai Kisinda
- Simon Badjie
- Jaclyn Bennet Denise Evans
- Elvira Monteiro
- Beate Kampmann
- Monica Davies
- Stefan Niemann
- Knut Lönnroth
- Issa Sabi
- Anna-Maria Mekota
- Olumuyiwa Owolabi
- Kamban Hirasen
- Salomão Manjate
- Tina Minja
- Alberto Machaze
- Salome Charalambous
- Mohamed I. M. Ahmed
- Michael Hoelscher
- Andrea Rachow
- Ben Dowsing
- Abdou Sillah
- Sofia Viegas
- Nyanda E. Ntinginya
- Narciso Macie
- Arlindo Machava
Institutions
- University of Dar es Salaam (TZ)
- University of the Witwatersrand (ZA)
- Karolinska Institutet (SE)
- Helmholtz Zentrum München (DE)
- LMU Klinikum (DE)
- Mbeya University of Science and Technology (TZ)
- Fraunhofer Institute for Translational Medicine and Pharmacology (DE)
- German Center for Infection Research (DE)
- MRC Unit the Gambia (GM)
- Aurum Institute (ZA)
- South African Sugarcane Research Institute (ZA)
- Research Center Borstel - Leibniz Lung Center (DE)
- Instituto Nacional de Saúde (MZ)
- Helen Joseph Hospital (ZA)
- Ministry of Health (MZ)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Communications Medicine
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1038/s43856-026-01424-w
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsches Zentrum für Infektionsforschung
- Bundesministerium für Bildung und Forschung