Characterizing the gut virome in ulcerative colitis and crohn’s disease: signatures of disease severity
Thus, IBD is associated with reduced virome diversity, loss of core protective phages, and selective enrichment of bacteriophages and eukaryotic viruses. These findings suggest that virome features may have potential as biomarkers for non-invasive diagnosis and severity stratification in IBD, requiring validation in larger and longitudinal cohorts.
Authors
- Seyed Mohammad Jazayeri (ORCID: https://orcid.org/0000-0002-2330-6921)
- Vahdat Poortahmasebi (ORCID: https://orcid.org/0000-0001-5409-2121)
- Mohammad Sabbaghian (ORCID: https://orcid.org/0000-0003-2452-8953)
- Nasim Izadi (ORCID: https://orcid.org/0000-0003-2401-9630)
- N Ebrahimi Daryani
- Ali Akbar Shekarchi
- Hossein Bannazadeh Baghi
- Shima Sadeghipour Marvi
- Arezou Azadi
- Hadi Ahmadi
- Masoud Shirmohammadi
Institutions
- Tabriz University of Medical Sciences (IR)
- Imam Khomeini Hospital (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Virology Journal
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1186/s12985-026-03091-8
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00