Portal Vein Diameter on Routine Clinical CT: Establishing Normals and Disease Associations
In this large, EHR-linked imaging cohort, the mean portal vein diameter on CT was 12.4 mm and varied with demographic and imaging factors. Larger diameter was associated with liver disease, portal hypertension, and subsequent development of varices and ascites, supporting use of portal vein diameter as a pragmatic screening or enrichment tool within multimodal clinical frameworks.
Authors
- MD PhD Terence Gade
- Daniel M. DePietro (ORCID: https://orcid.org/0000-0001-8984-1321)
- Renae Judy
- James Gee
- Penn Medicine Biobank
- Jeffrey Duda
Institutions
- Philadelphia VA Medical Center (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- medRxiv
- Published
- 2026-02-14
- DOI
- https://doi.org/10.64898/2026.02.11.26346009
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Defense
- University of Pennsylvania
- Georgia Clinical and Translational Science Alliance
- University of Pennsylvania Health System
- National Institutes of Health
- Perelman School of Medicine, University of Pennsylvania
- National Center for Advancing Translational Sciences