Prevalence and Spectrum of Chronic Liver Disease Among Patients Seeking Health Care in Ghana

We found a high prevalence of CLD, predominantly caused by HBV, MASLD and alcohol. We confirmed the use of transient elastography as a non-invasive and easily applicable tool in resource-limited settings. Our findings underscore the need for systematic screening of hospitalised patients, especially men, in sub-Saharan Africa. Comprehensive screening, treatment, vaccination and prevention programs for HBV, as the leading cause of chronic liver disease, are warranted.

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Publication Details

Journal
Liver International
Published
2026-02-14
DOI
https://doi.org/10.1111/liv.70538
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Prevalence and Spectrum of Chronic Liver Disease Among Patients Seeking Health Care in Ghana

Martha Holtfreter, Dieter Glebe, Anna Maria Eis‐Hübinger, Sabine Stauga et al.
Liver International
Liver Disease Diagnosis and Treatment
article

Prevalence and Spectrum of Chronic Liver Disease Among Patients Seeking Health Care in Ghana

Martha Holtfreter, Dieter Glebe, Anna Maria Eis‐Hübinger, Sabine Stauga, Felix Lehmann, Pia L. Roppert, Richard Odame Phillips, S. Schmiedel, Ohene Opare‐Sem, Kirsten Alexandra Eberhardt, Hans Martin Orth, S. Ehrhardt, Alexander Killer, Tom Luedde, Jan Felix Drexler, Ansgar Wilhelm Lohse, Sarah Wels, Torsten Feldt, Fred Stephen Sarfo, Christian Drosten
article en

Abstract

We found a high prevalence of CLD, predominantly caused by HBV, MASLD and alcohol. We confirmed the use of transient elastography as a non-invasive and easily applicable tool in resource-limited settings. Our findings underscore the need for systematic screening of hospitalised patients, especially men, in sub-Saharan Africa. Comprehensive screening, treatment, vaccination and prevention programs for HBV, as the leading cause of chronic liver disease, are warranted.

Liver InternationalVol. 46(3)
Johns Hopkins University (US), Universität Hamburg (DE), University Hospital Bonn (DE), Komfo Anokye Teaching Hospital (GH), Humboldt-Universität zu Berlin (DE), Düsseldorf University Hospital (DE), University Medical Center Hamburg-Eppendorf (DE), Institute of Virology of the Slovak Academy of Sciences (SK), Heinrich Heine University Düsseldorf (DE), Bernhard Nocht Institute for Tropical Medicine (DE), FH Aachen (DE)
Justus Liebig Universität Gießen, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Deutsche Forschungsgemeinschaft, Robert Koch Institut
Good health and well-being
Openalex Percentile: Top 55%
Liver Disease Diagnosis and Treatment
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