Serum VEGF levels may have a role in the assessment of treatment response and disease activity during TNFi therapy in patients with axSpA

In patients with axSpA, TNFi therapy significantly reduces serum VEGF levels and effectively reduces disease activity. VEGF has the potential to function as a dynamic biomarker that reflects the characteristics of the disease and the response to treatment.

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Publication Details

Journal
Modern Rheumatology
Published
2026-02-14
DOI
https://doi.org/10.1093/mr/roag004
Primary Topic
Spondyloarthritis Studies and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Serum VEGF levels may have a role in the assessment of treatment response and disease activity during TNFi therapy in patients with axSpA

Gökhan Kabadayi, M. Ozmen, Merve Güleç Yazır, Leyla Didem Kozacı et al.
Modern Rheumatology
Spondyloarthritis Studies and Treatments
article

Serum VEGF levels may have a role in the assessment of treatment response and disease activity during TNFi therapy in patients with axSpA

Gökhan Kabadayi, M. Ozmen, Merve Güleç Yazır, Leyla Didem Kozacı, Kübra Kaya, Dilek Solmaz, Servet Akar, Elif Durak Ediboğlu
article en

Abstract

In patients with axSpA, TNFi therapy significantly reduces serum VEGF levels and effectively reduces disease activity. VEGF has the potential to function as a dynamic biomarker that reflects the characteristics of the disease and the response to treatment.

Modern Rheumatology
Izmir Kâtip Çelebi University (TR), Ankara Yıldırım Beyazıt University (TR), Gazi University (TR)
Good health and well-being
Openalex Percentile: Top 57%
Spondyloarthritis Studies and Treatments
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