Involvement of SWAP-70 in proteolipid protein-induced experimental autoimmune encephalomyelitis
SWAP-70 appears to have an autoimmunity-suppressing effect in the PLP-EAE model, likely mediated by inhibiting follicular B cells. These findings propose a novel mechanism by which SWAP-70 might be involved in autoimmunity and endorse SWAP-70 as a potential target in novel MS-treatment strategies.
Authors
- Gizem Koral (ORCID: https://orcid.org/0000-0001-9484-9440)
- VUSLAT YILMAZ
- Recai Türkoğlu (ORCID: https://orcid.org/0000-0001-7685-4633)
- Yasemin Gursoy Ozdemir
- ERDEM TÜZÜN
- CANAN ULUSOY
- CEM İSMAİL KÜÇÜKALİ
- FATMA AKPUNAR SALMAN
- MELİS ŞEN
- EMİNE ŞEKERDAĞ KILIÇ
Institutions
- Koç University (TR)
- HUN-REN Institute of Experimental Medicine (HU)
- Haydarpaşa Numune Eğitim ve Araştırma Hastanesi (TR)
Publication Details
- Journal
- TURKISH JOURNAL OF MEDICAL SCIENCES
- Published
- 2026-02-12
- DOI
- https://doi.org/10.55730/1300-0144.6161
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00