Glymphatic system dysfunction and cognitive impairment in post-chemotherapy AML: A novel DTI-ALPS index study
Post-chemotherapy AML patients exhibit glymphatic system dysfunction and cognitive decline, with a significant association between these alterations. Impairment in glymphatic function, as suggested by these biomarkers, may contribute to cognitive deficits in this context. The DTI-ALPS index and BG-PVS volume represent potential neuroimaging biomarkers, providing new insights into chemotherapy-related cognitive impairment in AML.
Authors
- Yanan Huang
- Dongxue Qin (ORCID: https://orcid.org/0000-0003-1084-3901)
- Honghai Chen
- Zilin Xu
- Zhijie Kang
- Peng Li
- Yifei Zhang
- Jinsong Yan
- Yue Zhao
- Ying Wang
- Chuang Sun
- Yuhai Cao
- Yan Yang
- Ying Li
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1016/j.brainresbull.2026.111777
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00