Outcomes of Mechanical Mitral Valve Replacement with Preservation of Posterior Leaflet in Patients with Reduced Left Ventricular Function
Background: Compromised left ventricular function presents unique challenges during mitral valve surgery. Recent evidence suggests that subvalvular apparatus preservation might enhance postoperative recovery in high-risk populations. Methods: This prospective observational investigation (Hue Central Hospital, March 2015–September 2016) evaluated 87 patients undergoing mechanical mitral valve replacement with posterior leaflet preservation. Participants were stratified into two groups: reduced ejection fraction (EF ≤ 50%, n = 38) and preserved EF (>50%, n = 49). Comprehensive clinical and echocardiographic assessments were conducted at 1, 3, 6, and 12 months postoperatively. Statistical analysis employed parametric and non-parametric methodologies, with survival analyzed via Kaplan–Meier techniques. Results: The reduced EF cohort demonstrated significant improvement in contractile performance from 48.8 ± 5.2% preoperatively to 61.6 ± 7.2% at 12 months (p < 0.05). Ventricular dimensions decreased notably from 59.2 ± 6.6 mm to 47.6 ± 4.0 mm (p < 0.05). Hospital mortality was 2.3% (2 patients). Twelve-month survival rates reached 94.66% and 97.96% for reduced and preserved EF groups, respectively, without significant inter-group differences (p = 0.42). All surviving participants achieved functional status in NYHA class I or II. Conclusions: Mechanical mitral valve replacement with posterior leaflet preservation represents an effective approach for patients with reduced ventricular performance, promoting substantial improvement in cardiac function and excellent clinical outcomes.
Authors
- Bao Tran (ORCID: https://orcid.org/0009-0009-7826-0244)
- Duong Minh Vu (ORCID: https://orcid.org/0009-0002-6037-3848)
- Dung Van Nguyen
- Viet Anh Le
- Vinh Duc An Bui
- Phu Duc Bui
- Dung Tien Nguyen
- Nam Van Nguyen
Institutions
- Hue Central Hospital (VN)
- Vinmec Times City International Hospital (VN)
- Vietnam Military Medical University (VN)
- Toyama University Hospital (JP)
- Hung Vuong Hospital (VN)
- 108 Military Central Hospital (VN)
- Pham Ngoc Thach Hospital (VN)
Publication Details
- Journal
- Surgeries
- Published
- 2026-02-14
- DOI
- https://doi.org/10.3390/surgeries7010024
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00