Outcomes of Mechanical Mitral Valve Replacement with Preservation of Posterior Leaflet in Patients with Reduced Left Ventricular Function

Background: Compromised left ventricular function presents unique challenges during mitral valve surgery. Recent evidence suggests that subvalvular apparatus preservation might enhance postoperative recovery in high-risk populations. Methods: This prospective observational investigation (Hue Central Hospital, March 2015–September 2016) evaluated 87 patients undergoing mechanical mitral valve replacement with posterior leaflet preservation. Participants were stratified into two groups: reduced ejection fraction (EF ≤ 50%, n = 38) and preserved EF (>50%, n = 49). Comprehensive clinical and echocardiographic assessments were conducted at 1, 3, 6, and 12 months postoperatively. Statistical analysis employed parametric and non-parametric methodologies, with survival analyzed via Kaplan–Meier techniques. Results: The reduced EF cohort demonstrated significant improvement in contractile performance from 48.8 ± 5.2% preoperatively to 61.6 ± 7.2% at 12 months (p < 0.05). Ventricular dimensions decreased notably from 59.2 ± 6.6 mm to 47.6 ± 4.0 mm (p < 0.05). Hospital mortality was 2.3% (2 patients). Twelve-month survival rates reached 94.66% and 97.96% for reduced and preserved EF groups, respectively, without significant inter-group differences (p = 0.42). All surviving participants achieved functional status in NYHA class I or II. Conclusions: Mechanical mitral valve replacement with posterior leaflet preservation represents an effective approach for patients with reduced ventricular performance, promoting substantial improvement in cardiac function and excellent clinical outcomes.

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Journal
Surgeries
Published
2026-02-14
DOI
https://doi.org/10.3390/surgeries7010024
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
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article

Outcomes of Mechanical Mitral Valve Replacement with Preservation of Posterior Leaflet in Patients with Reduced Left Ventricular Function

Bao Tran, Duong Minh Vu, Dung Van Nguyen, Viet Anh Le et al.
Surgeries
Cardiac Valve Diseases and Treatments
article

Outcomes of Mechanical Mitral Valve Replacement with Preservation of Posterior Leaflet in Patients with Reduced Left Ventricular Function

Bao Tran, Duong Minh Vu, Dung Van Nguyen, Viet Anh Le, Vinh Duc An Bui, Phu Duc Bui, Dung Tien Nguyen, Nam Van Nguyen
article en

Abstract

Background: Compromised left ventricular function presents unique challenges during mitral valve surgery. Recent evidence suggests that subvalvular apparatus preservation might enhance postoperative recovery in high-risk populations. Methods: This prospective observational investigation (Hue Central Hospital, March 2015–September 2016) evaluated 87 patients undergoing mechanical mitral valve replacement with posterior leaflet preservation. Participants were stratified into two groups: reduced ejection fraction (EF ≤ 50%, n = 38) and preserved EF (>50%, n = 49). Comprehensive clinical and echocardiographic assessments were conducted at 1, 3, 6, and 12 months postoperatively. Statistical analysis employed parametric and non-parametric methodologies, with survival analyzed via Kaplan–Meier techniques. Results: The reduced EF cohort demonstrated significant improvement in contractile performance from 48.8 ± 5.2% preoperatively to 61.6 ± 7.2% at 12 months (p < 0.05). Ventricular dimensions decreased notably from 59.2 ± 6.6 mm to 47.6 ± 4.0 mm (p < 0.05). Hospital mortality was 2.3% (2 patients). Twelve-month survival rates reached 94.66% and 97.96% for reduced and preserved EF groups, respectively, without significant inter-group differences (p = 0.42). All surviving participants achieved functional status in NYHA class I or II. Conclusions: Mechanical mitral valve replacement with posterior leaflet preservation represents an effective approach for patients with reduced ventricular performance, promoting substantial improvement in cardiac function and excellent clinical outcomes.

SurgeriesVol. 7(1)
Hue Central Hospital (VN), Vinmec Times City International Hospital (VN), Vietnam Military Medical University (VN), Toyama University Hospital (JP), Hung Vuong Hospital (VN), 108 Military Central Hospital (VN), Pham Ngoc Thach Hospital (VN)
Good health and well-being
Openalex Percentile: Top 58%
Cardiac Valve Diseases and Treatments
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